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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPX2
All Species:
12.73
Human Site:
S356
Identified Species:
28
UniProt:
Q9ULW0
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULW0
NP_036244.2
747
85653
S356
D
D
I
N
L
L
P
S
K
S
S
V
T
K
I
Chimpanzee
Pan troglodytes
XP_001153533
746
85517
S355
D
D
I
N
L
L
P
S
K
S
S
V
T
K
I
Rhesus Macaque
Macaca mulatta
XP_001109645
746
85683
S355
D
D
I
N
L
L
P
S
K
S
S
V
T
K
I
Dog
Lupus familis
XP_850934
748
86144
S357
D
D
I
T
L
L
P
S
K
S
A
G
L
K
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_082385
745
85876
K358
D
E
S
L
L
P
S
K
S
V
N
K
I
A
R
Rat
Rattus norvegicus
NP_001101260
744
85432
K356
D
E
S
L
L
P
S
K
P
V
N
K
I
V
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516385
623
69684
F327
T
V
P
K
S
P
A
F
A
L
K
N
R
M
R
Chicken
Gallus gallus
NP_989768
739
85048
A355
S
D
E
G
P
A
P
A
K
P
V
K
A
R
L
Frog
Xenopus laevis
NP_001086751
715
81991
P336
L
K
P
K
L
T
N
P
K
T
P
L
L
Q
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798362
948
108486
K556
H
R
D
N
S
M
H
K
E
E
V
P
K
P
R
Poplar Tree
Populus trichocarpa
XP_002327911
811
91572
I364
H
D
G
P
A
S
V
I
Q
R
K
P
K
L
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.5
90.3
N.A.
79.2
79.1
N.A.
40.1
57.5
53.8
N.A.
N.A.
N.A.
N.A.
N.A.
31.6
Protein Similarity:
100
99.3
98.6
93.9
N.A.
87.6
87.4
N.A.
53
72.5
70
N.A.
N.A.
N.A.
N.A.
N.A.
49.4
P-Site Identity:
100
100
100
73.3
N.A.
13.3
13.3
N.A.
0
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
80
N.A.
26.6
26.6
N.A.
0
40
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
20.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
10
10
0
10
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
55
55
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
19
10
0
0
0
0
0
10
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
10
0
0
0
0
0
0
0
10
0
0
0
% G
% His:
19
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
37
0
0
0
0
10
0
0
0
0
19
0
37
% I
% Lys:
0
10
0
19
0
0
0
28
55
0
19
28
19
37
0
% K
% Leu:
10
0
0
19
64
37
0
0
0
10
0
10
19
10
10
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
37
0
0
10
0
0
0
19
10
0
0
0
% N
% Pro:
0
0
19
10
10
28
46
10
10
10
10
19
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
10
0
0
10
10
37
% R
% Ser:
10
0
19
0
19
10
19
37
10
37
28
0
0
0
0
% S
% Thr:
10
0
0
10
0
10
0
0
0
10
0
0
28
0
19
% T
% Val:
0
10
0
0
0
0
10
0
0
19
19
28
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _